Continuous production from powder to capsule
From May 7 to 13, Syntegon Technology showcases its long-standing processing and packaging expertise for solid dosage forms at the Virtual Show. The new Sepion coater series, which is available in six sizes, marks the beginning of the novelties. Visitors to the virtual event can also experience continuous production from powders to the finished capsule with the specially developed X-key principle. In addition, the new “Automated Process Development” (APD) tool automatically calculates optimal parameters for capsule filling processes in very short times.
Syntegon presents its new Sepion coater series for the first time. “We have combined decades of experience of the former Manesty product brand with the expertise in tablet coating and process technology of the Hüttlin product brand. By introducing the new Sepion series we can offer our customers an ideal combination of experience and innovation”, says Fritz-Martin Scholz, product manager at Syntegon. The state-of-the-art equipment for tablet coating enables closed material handling during filling, sampling and emptying. This makes the Sepion coaters suited for the coating of tablets with highly potent active ingredients, as well as for sugar coating. The optimized drum geometry with its sophisticated spraying system offers better guidance of the process air and shorter processing times. Moreover, the coaters feature an automatically adjustable spray arm and ensure high flexibility from 10 to 100 percent batch size. The fully equipped Sepion coaters are available in six sizes from 175 and 250 to 350 and 500 to 750 and 1,000-liters capacity.
The continuous production of oral solid dosage forms is an unbroken trend. The Xelum production platform and Xelum R&D unit are based on the same principle developed by the Hüttlin product brand: as opposed to the common complex mass flow rate, excipients and active ingredients are dosed as a discrete mass. This makes it possible to dose even smallest amounts of APIs of less than one percent reliably. At the Virtual Show, visitors can find out how the Xelum R&D doses, mixes and granulates individual packages, so-called X-keys. The packages continuously run through the process chain and are pneumatically transported to the GKF 720 capsule filling machine and filled into capsules.
As another highlight, Syntegon Technology presents a number of new software features, including the “Automated Process Development” (APD) tool to determine optimum parameters for capsule filling processes. “While such manual evaluations used to take days or even weeks, the APD tool not only achieves faster but also more precise results”, Matthias Mössinger, product manager at Syntegon Technology, explains.
By determining correlations between parameters critical to material, quality and processes, the tool ensures a better understanding of the process – which in turn has a positive effect on product quality. “Investments in tools such as the APD during the process development phase will be rewarded in commercial production”, Mössinger says. In the future, the APD tool will be available for both capsules and tablets.
Additionally, Syntegon offers customers machines and lines for secondary packaging of their solid pharmaceuticals, as well as comprehensive Track and Trace solutions. The portfolio is rounded off by comprehensive services along the entire machine life cycle.
Find more on Syntegon Technology’s Virtual Show from May 7 to 13 and learn more about the novelties.
The Covid-19 pandemic led to the country-wide lockdown on 25 March 2020. It will be two years tomorrow as I write this. What have we learned in this time? Maybe the meaning of resilience since small companies like us have had to rely on our resources and the forbearance of our employees as we have struggled to produce our trade platforms.
The print and packaging industries have been fortunate, although the commercial printing industry is still to recover. We have learned more about the digital transformation that affects commercial printing and packaging. Ultimately digital will help print grow in a country where we are still far behind in our paper and print consumption and where digital is a leapfrog technology that will only increase the demand for print in the foreseeable future.
Web analytics show that we now have readership in North America and Europe amongst the 90 countries where our five platforms reach. Our traffic which more than doubled in 2020, has at times gone up by another 50% in 2021. And advertising which had fallen to pieces in 2020 and 2021, has started its return since January 2022.
As the economy approaches real growth with unevenness and shortages a given, we are looking forward to the PrintPack India exhibition in Greater Noida. We are again appointed to produce the Show Daily on all five days of the show from 26 to 30 May 2022.
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